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Liver, Pancreas, Biliary Cancer Clinical Trials

The goal of our clinical research program at Virginia Mason Franciscan Health is to provide you with a research option at every step of their disease, from initial diagnosis to long-term follow-up of liver disease.

The Center for Digestive Health research program offers clinical trials in various chronic liver diseases in conjunction with Benaroya Research Institute and the Liver Center of Excellence.

Chronic liver disease studies

Pancreatic studies

Pancreatic cancer studies

Alternating neoadjuvant Gemcitabine-Nab-Paclitaxel and nal-IRI with 5-Fluorouracil and folinic acid (Leucovorin) regimens in resectable and borderline resectable pancreatic cancer, A Pilot Study

Gemcitabine and Nab-Paclitaxel in Pancreatic Adenocarcinoma with Positive Peritoneal Cytology as a Sole Metastatic Site

Pivotal, randomized, open-label study of Tumor Treating Fields (TTFields, 150kHz) concomitant with gemcitabine and nab-paclitaxel for front-line treatment of locally-advanced pancreatic adenocarcinoma

Distal pancreatectomy, minimally invasive or open, for malignancy (DIPLOMA): a randomized controlled, multicenter, non-inferiority trial.

A Phase 3, Randomized, Double-Blind Study of Pamrevlumab or Placebo in combination with Gemcitabine Plus Nab-paclitaxel as Neoadjuvant Treatment in Patients with Locally Advanced, Unresectable Pancreatic Cancer


A Phase 1a/b Dose-Escalation Study Followed by Expansion Cohorts of NGM120, a GFRAL Antagonist Monoclonal Antibody Blocking GDF15 Signaling, in Subjects With Advanced Solid Tumors and Pancreatic Cancer Using Combination Therapy

A Phase I/II Study of MCLA-128, a full length IgG1 Bispecific Antibody Targeting HER2 and HER3, in Patients with Solid Tumors

A Study to Evaluate the Safety, Tolerability, and Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer, and Other Advanced Solid Tumors

Alternative Neoadjuvant Chemotherapy in Resectable and Borderline Resectable Pancreatic Cancer

To learn about clinical trials in pancreatic cancer across the country, view the PanCAN Clinical Trials.

Endoscopy clinical trials

Find a clinical trial

To talk with a clinical research coordinator about non-cancer clinical research trials, call the Center for Digestive Health hotline at 206-341-1295.

To talk with a clinical research coordinator about clinical research trials related to liver, pancreatic or biliary cancer, call the Cancer Clinical Research Unit Research hotline at 206-287-6270.